Passengers are being urged to check their journeys after Network Rail confirmed part of the Marston Vale Line will remain closed to trains until Tuesday 3 March.
The closure follows a level crossing fault between Ridgmont and Bedford.
A shuttle train service will operate between Bletchley and Ridgmont on Saturday and Monday. Replacement buses will serve stations between Bedford and Ridgmont.
There is no Sunday service on the Marston Vale Line.
Lawrence Bowman, customer experience director for London Northwestern Railway, which operates services on the Marston Vale Line, said:
"We apologise to our customers for the ongoing disruption to journeys on the Marston Vale Line while Network Rail engineers continue to work in the affected area.
"The safety of our passengers and staff is of paramount importance and we cannot allow trains to run until we receive the all-clear.
"Passengers are advised to check live travel information before setting out and to leave more time for their journeys, particularly if they are travelling between Bedford and Ridgmont."
Any passengers delayed by 15 minutes or more as a result of the issue can claim compensation via the Delay Repay scheme at www.lnr.uk/delayrepay
A further update on the progress of the repair work will follow on Monday - for the latest live travel information visit www.lnr.uk/plan
About West Midlands Trains
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West Midlands Trains operates both West Midlands Railway and London Northwestern Railway services.
- London Northwestern Railway services operate between Liverpool and Birmingham, and on the West Coast mainline to and from London Euston.
- West Midlands Railway services operate to destinations across the West Midlands via Birmingham New Street.
The West Midlands Trains franchise started on 10 December 2017 and will run until 2025/26.
West Midlands Trains operates 1,300 services a day, manages 150 stations and provides over 80 million passenger journeys a year. Over the course of the franchise, West Midlands Trains will be investing £1 billion into the rail network to deliver new trains, improved routes and station upgrades. This will include 400 new train carriages across the network and space for an extra 85,000 passengers into Birmingham and London at peak times.
The franchise is a joint venture between Abellio (70.1% share) and East Japan Railway Company / Mitsui & Co., Ltd (29.9% share in a 50:50 split). Abellio is the international passenger transport subsidiary of the Dutch national railway company, Nederlandse Spoorwegen. In the UK, Abelllio operates ScotRail and Greater Anglia train services, Merseyrail services in a joint venture with Serco and buses through Abellio London. For more information visit www.abellio.com
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